Yanagi: Fast and interpretable segment-based alternative splicing and gene expression analysis
نویسندگان
چکیده
منابع مشابه
Structure, alternative splicing, and expression of the human RGS9 gene.
An isoform of RGS9 was recently identified as the GTPase activating protein in bovine and mouse rod and cone photoreceptors. To explore the potential role of the RGS9 gene in human retinal disease, we determined its exon/intron arrangement, and investigated its expression in human retina. The results show that the gene, located on 17q24, consists of 19 exons and spans more than 75kb of genomic ...
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Motivation: Interpretation of classification models derived from gene expression data is usually not simple, yet it is an important aspect in the analytical process. We investigate the performance of small rule-based classifiers based on fuzzy logic in five data sets that are different in size, laboratory origin, and biomedical domain. Results: The classifiers resulted in rules that can be read...
متن کاملSmall, fuzzy and interpretable gene expression based classifiers
MOTIVATION Interpretation of classification models derived from gene-expression data is usually not simple, yet it is an important aspect in the analytical process. We investigate the performance of small rule-based classifiers based on fuzzy logic in five datasets that are different in size, laboratory origin and biomedical domain. RESULTS The classifiers resulted in rules that can be readil...
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The performance of gene finding from genome sequences strongly depends on the accuracy of splice site prediction. Recent gene finding programs, however, still do not reach enough levels. To improve the accuracy of splice site prediction, it is required to understand the splicing mechanism and to make a model from clear experimental evidences. For this purpose, genomic full-length precursor mRNA...
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BACKGROUND The wild barley Hordeum chilense Roem. et Schult. is a valuable source of genes for increasing carotenoid content in wheat. Tritordeums, the amphiploids derived from durum or common wheat and H. chilense, systematically show higher values of yellow pigment colour and carotenoid content than durum wheat. Phytoene synthase 1 gene (Psy1) is considered a key step limiting the carotenoid ...
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ژورنال
عنوان ژورنال: BMC Bioinformatics
سال: 2019
ISSN: 1471-2105
DOI: 10.1186/s12859-019-2947-6